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Ex-OpenAI team raises $300M to build AI scientists

PLUS: Mira Murati's stealth lab ships its first product, Microsoft's chip plan, and Peloton's AI coach

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Good morning, AI enthusiast.

A new startup from ex-OpenAI and Google DeepMind talent has raised a massive $300M to build 'AI scientists'. The venture, Periodic Labs, is looking to move AI beyond analyzing existing data to actively running its own physical experiments.

By creating new proprietary data through autonomous labs, this initiative represents a major shift from an AI that learns from the past to one that actively discovers the future. Could this new approach fundamentally change the pace of scientific breakthroughs?

In today's AI recap:

  • Ex-OpenAI team's $300M 'AI scientist' lab

  • Mira Murati's lab ships first dev product

  • Microsoft's custom AI chip strategy

  • Peloton's new AI-powered coach

  • 8 trending AI Tools

The $300M AI Scientist

The Recap: Periodic Labs has emerged from stealth with a massive $300M seed round to build "AI scientists." The new startup, led by ex-OpenAI and Google DeepMind researchers, aims to accelerate discovery by having AI run its own physical experiments.

Unpacked:

  • The core idea is that AI has nearly exhausted the internet's finite data; the next frontier requires creating new knowledge through real-world interaction, not just analyzing existing text.

  • An all-star founding team gives the venture huge credibility, including Liam Fedus, who helped create ChatGPT at OpenAI, and Ekin Dogus Cubuk, who led materials science at Google DeepMind.

  • The company will build autonomous labs to create a closed-loop system, running its own experiments and using the proprietary data—including failures—to train more capable models.

Bottom line: This initiative represents a fundamental shift from AI that learns from the past to AI that actively discovers the future. If successful, it could compress decades of scientific research in fields like materials science and energy into a fraction of the time.

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Mira Murati's AI Lab Ships

The Recap: Thinking Machines Lab, the stealth startup from former OpenAI CTO Mira Murati, has launched its first product: Tinker. It's a powerful new API designed to simplify how developers create and fine-tune custom AI models.

Unpacked:

  • Tinker allows developers to write training loops in Python on their local machine, while Thinking Machines handles the complex job of running them on distributed GPUs.

  • The tool abstracts away the difficult infrastructure challenges of post-training, giving researchers and developers more control over the core algorithm and data.

  • It aims to bring frontier tools to a wider audience, enabling more people to experiment with and customize cutting-edge open models for their specific needs.

Bottom line: Tinker lowers the technical barrier for building specialized AI, shifting model creation capabilities from a few large labs to more individual researchers and developers. This could lead to a wave of custom AI tools built for niche industries and unique problems.

AI Training

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Microsoft's Silicon Strategy

The Recap: Microsoft's CTO Kevin Scott confirmed the company's long-term goal is to primarily run its data centers on its own custom-designed chips. This strategic shift aims to reduce reliance on NVIDIA and control the entire AI hardware stack.

Unpacked:

  • The strategy goes beyond just silicon; Microsoft aims to design the full data center system, including networking and cooling, to optimize performance for specific AI workloads.

  • This builds on existing custom chips like the Azure Maia AI Accelerator and is enabled by innovations like microfluidic cooling, which brings liquid coolant directly onto chips.

  • The move reflects an industry-wide race for vertical integration, with Google and Amazon also developing custom chips to navigate the massive crunch in available AI compute capacity.

Bottom line: Controlling the entire hardware stack gives Microsoft the ability to build more efficient AI infrastructure, becoming a critical advantage for delivering next-generation AI services at scale.

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Peloton's AI Coach

The Recap: Peloton is embedding an AI-powered personal coach into its new lineup of bikes and treadmills. The feature, Peloton IQ, uses a movement-tracking camera to provide real-time feedback on exercise form.

Unpacked:

  • The new computer vision system analyzes your form, counts reps, and provides personalized workout advice to help you improve.

  • This feature evolves from Peloton's previous standalone camera, the Guide, integrating the tech directly into the primary equipment based on user feedback.

  • This is the first major product launch under new CEO Peter Stern, aimed to kickstart growth and broaden Peloton's reputation beyond cardio.

Bottom line: Peloton is betting that integrating AI coaching directly into its hardware can make personalized training more accessible at home. This move is a major test of whether AI-driven features can revive the brand and justify premium prices.

The Shortlist

Google appears to be blocking its AI Overview feature from answering queries about Donald Trump’s cognitive health while still generating summaries for the same questions about Joe Biden.

Anthropic revealed in a safety analysis that its new Claude Sonnet 4.5 model shows signs of situational awareness, occasionally recognizing it was being tested and asking evaluators to be honest about their intentions.

Stanford released OpenTSLM, a new class of foundation models designed to natively handle time-series data, enabling direct reasoning and forecasting over temporal signals like sensor pulses or price ticks.

Yale found in a new study that generative AI has had no discernible disruptive impact on the U.S. labor market since ChatGPT's launch, undercutting widespread fears of immediate job erosion.

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David, Lucas, Mitchell — The Recap editorial team